Nebulin is a large protein found in skeletal muscle that plays a crucial role in sarcomere structure and muscle function. Nebulin is thought to act as a molecular ruler, determining the length of thin filaments in muscle fibers. It also interacts with other proteins in the sarcomere to help regulate muscle contraction. Research on nebulin function seeks to understand how this protein contributes to muscle health and function, and how mutations in nebulin can lead to muscle diseases such as nemaline myopathy. Studies on nebulin function may also have implications for developing new therapies for muscle-related disorders.